Tirzepatide is a synthetic 39-amino acid linear peptide based on the native glucose-dependent insulinotropic polypeptide (GIP) sequence, modified with a C20 fatty diacid moiety for albumin binding and extended half-life. It functions as a dual incretin receptor agonist, acting as a full agonist at the GIP receptor and a biased partial agonist at the GLP-1 receptor, favoring G-protein-mediated cAMP signaling over beta-arrestin recruitment. In research contexts, tirzepatide is used to study dual incretin receptor pharmacology, insulin secretion dynamics, glucagon suppression, appetite regulation, and adipose tissue metabolism, including branched-chain amino acid catabolism in brown adipose tissue. Sold for qualified laboratory and research purposes only. Not for human or animal consumption.