Semax is a synthetic peptide derived from the 4–10 fragment of adrenocorticotropic hormone (ACTH), with the sequence Met-Glu-His-Phe-Pro-Gly-Pro. It was originally developed as a research tool for studying melanocortin receptor signaling and has since been investigated for its effects on BDNF and NGF expression, cerebral blood flow regulation, and serotonergic/dopaminergic system modulation. Published research includes models of cerebral ischemia, cognitive function, and immune response modulation. Semax also demonstrates high affinity for copper(II) ions, making it a subject of interest in metallopeptide chemistry. Sold for qualified laboratory and research purposes only. Not for human or animal consumption.